Birdshot retinochoroidopathy review Revisão sobre retinocoroidopatia do tipo “ birdshot ”
نویسنده
چکیده
Birdshot retinochoroidopathy (BSRC) is a distinct type of posterior uveitis originally described in the 1940s. Its characteristics include minimal anterior segment inflammation and diffuse posterior choroidopathy with vitritis and retinal vasculitis. The precise etiology of this disease is yet to be elucidated. However, various treatment modalities have been employed with the ultimate goal of durable remission of this vision threatening intraocular disease. The purpose of this review is not only to emphasize the importance of recognizing BSRC, but also to discuss the new discoveries, immune mediators, current and new therapies, and techniques applied to monitor and accomplish disease remission.
منابع مشابه
Ultrahigh resolution optical coherence tomography of birdshot retinochoroidopathy.
Birdshot retinochoroidopathy is a rare inflammatory eye disease with typical clinical presentation and strong association with the HLA-A29 allele. Characteristic appearances on fluorescein angiogram (FA), indocyanine green (ICG) angiography, and electroretinogram (ERG) have been described. However, histopathology of the disease has been rare. 3 The following case is an example of birdshot retin...
متن کاملWhy birdshot retinochoroiditis should rather be called ‘HLA-A29 uveitis’?
BIRDSHOT RETINOCHOROIDITIS: THE ORIGINS OF THE DISEASE NAME Birdshot retinochoroiditis (BRC) is a uveitis predominantly affecting the posterior segment of the eye with dual, independent retinal and choroidal inflammation and almost only seen in Caucasians. 2 Ryan and Maumenee first described the bilateral retinochoroidal inflammatory disease in early 1980, reporting on 13 patients. These author...
متن کاملBirdshot Retinochoroidopathy
Birdshot retinochoroidopathy (BSRC) is an uncommon, but well-characterized chronic, bilateral posterior uveitis, which is uniquely associated with the human leukocyte antigen-A29 phenotype. The disease presents predominantly in middle-aged Caucasian females who complain of blurred vision, floaters, photopsias, paracentral scotomas and nyctalopia. While autoimmune mechanisms are thought to play ...
متن کاملHistopathology of birdshot retinochoroidopathy.
HIGHLIGHT Histopathology of birdshot retinochoroidopathy Birdshot retinochoroidopathy is a chronic posterior segment inflammatory disease with a characteristic clinical presentation and strong correlation with the HLA-A29 antigen. 1 2 In this report, we describe the his-topathological findings in the eye of a patient with this disease. A 49 year old white man was referred to the Proctor Medical...
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